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Welcome to our site
We aim to decipher how biological macromolecules interact with each other to accomplish their function. We carry out computer simulations at different levels of resolution and complexity to achieve this goal.

Our group has been established in 2017 at the University of Los Andes (Bogotá, Colombia) in tandem with the Max Planck Institute for Medical Research (Heidelberg, Germany). Here, you will find information about who we are, our research interests, publications, and scientific activities.

Mechanical Forces in Biology:
Theory and Simulation

Universidad de los Andes
Bogotá, Colombia
September 30–October 2, 2019

Info. and registration here

News archive [ ]
  • January 8, 2019. Our article about GROmaρs has been published in biophysical journal, computational tools section. Continue reading here.
  • October 22, 2018. A topical review on complex lipid mixtures, which is following a CECAM meeting, appeared published in the Journal of Membrane Biology. Continue reading here.
  • October 18, 2018. Within the SHENC collaboration, the structure of the von Willebrand factor C4 domain has been determined and published in the Blood journal. Continue reading here.
  • September 5, 2018. The meeting of the Colombian Max Planck Tandem groups, hosted by us, has been highlighted in the last issue of the Max Planck Research Magazine. Page 83 here.
  • August 28, 2018: Our school "Computer simulations of biological membranes and free energy calculations of biomolecular systems, took place at UniAndes on August 13-17, 2018. Photo of the participants:
  • June 22, 2018 . Our article on mechano-redox control of integrin de-adhesion together with Philip Hogg, Frauke Gräter and coworkers was published in eLife. Continue reading here.
  • June 18, 2018 . Our article on the stability of biological membranes upon mechanical indentation was published in JPCB. Continue reading here.
  • June 3, 2018 . First meeting of the Colombian Max Planck Tandem Groups, June 1-3, 2018, UNIANDES. Photo of the participants:
  • March 7, 2018. Our article on the role of disulfide bonds as swich of blood proteins in collaboration with Philip Hogg and coworkers was published in Science Advances. Continue reading here.
  • March 5, 2018. Colloquium on membranes at the University of Los Andes in YouTube.
  • March 2, 2018. Our course on molecular dynamics simulations of biomolecules was a complete success. Thank you all for your participation.
    More info here
  • August 30, 2017. Our article about the propagation of mechanical stress through biological bilayers was published in JACS. Continue reading here.

  • August 29, 2017. Our article about the accessibility of disulfide bonds in protein domains was published in Scientific Reports. continue reading here.

  • June 21, 2017. Our article about the effect of temperature on the dynamics of a gated-yeast aquaporin appeared published today in Scientific Reports.
Principal investigator: Dr. Camilo Aponte-Santamaría